Product Description for BUB3
BUB3.
Presentation: Purified
Presentation: Purified
Properties for BUB3
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | Mitotic checkpoint protein BUB3 |
| Presentation | Purified |
| Molecular weight | 39.5 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | Mitotic checkpoint protein BUB3, also known as BUB3, is a conserved component of the mitotic spindle assembly complex (MCC). The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. BUB3 is essential for the kinetochore localization of BUB1 and BUBR1. BUB3 is involved in the essential spindle checkpoint pathway that operates during early embryogenesis. In addition, BUB3 plays a role in regulating the establishment of correct kinetochore-microtubule attachments. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Martinez Exposito M J., et al. (1999) Proc Natl Acad Sci USA. 96:8493-8498.Warren C D., et al. (2002) Mol Biol Cell. 13:3029-3041. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Description |
|
| Format |
|
Compare Products
You have no items to compare.
My Cart
You have no items in your shopping cart.
