Dysadherin / FXYD5 (22-145, His-tag) - AR50792PU-S

Product Description for Dysadherin / FXYD5

Dysadherin / FXYD5.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	DYSAD, FXYD domain-containing ion transport regulator 5, IWU1
Presentation	Purified
Molecular weight	16.1 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q96DB9
Purity	> 95 % by SDS - PAGE
Background	FXYD domain-containing ion transport regulator 5, also known as FXYD5, is a cancer-associated cell membrane glycoprotein which belongs to the FXYD family. FXYD5 is involved in down-regulation of E-cadherin, which plays important roles in tumor development and metastasis. It is present in spleen, lung, skeletal muscle, and testis tissue, and maps to human chromosome 19q13.2.
Concentration	0.5 mg/ml (determined by BCA assay)
General Readings	Shimamura T., et al. (2003) J Clin Oncol. 21:659-667Sato H., et al. (2003) Metab. 9: 4407-4412.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human FXYD5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSQTLKDTT SSSSADSTIM DIQVPTRAPD AVYTELQPTS PTPTWPADET PQPQTQTQQL EGTDGPLVTD PETHKSTKAA HPTDDTTTLS ERPSPSTDVQ TDPQTLKPSG FHEDDPFFYD EHTLRKR` Molecular weight: (147aa) confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT Purity: >95% by SDS - PAGE State: Liquid purified protein Purified