Product Description for YOD1
YOD1.
Presentation: Purified
Presentation: Purified
Properties for YOD1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 20 µg |
| Synonyms | DUBA-8, DUBA8, HIN-7, HIN7, HIV-1-induced protease 7, OTU domain-containing protein 2, OTUD2, Ubiquitin thioesterase OTU1 |
| Presentation | Purified |
| Molecular weight | 40.7 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | YOD1 is a highly conserved deubiquitinating enzyme of the ovarian tumor (otubain) family, whose function has yet to be assigned in mammalian cells. YOD1 is a constituent of a multiprotein complex with p97 as its nucleus, suggesting a functional link to a pathway responsible for the dislocation of misfolded proteins from the endoplasmic reticulum. Expression of a YOD1 variant deprived of its deubiquitinating activity imposes a halt on the dislocation reaction, as judged by the stabilization of various dislocation substrates. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Ernst,R., et al. (2009) Mol. Cell 36 (1), 28-38 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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