CRLF2 (23-231, His-tag) - AR50846PU-S

Product Description for CRLF2

CRLF2.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	Cytokine receptor-like 2, Cytokine receptor-like factor 2, IL-XR, ILXR, TSLPR, Thymic stromal lymphopoietin protein receptor
Presentation	Purified
Molecular weight	26.6 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9HC73
Purity	> 85 % by SDS - PAGE
Background	CRLF2 is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Chen,I.M., et al. (2012) Blood 119 (15), 3512-3522Haslam,K., et al. (2011) Int J Lab Hematol 33 (6), E17-E19
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human CRLF2 protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSQGGAAEG VQIQIIYFNL ETVQVTWNAS KYSRTNLTFH YRFNGDEAYD QCTNYLLQEG HTSGCLLDAE QRDDILYFSI RNGTHPVFTA SRWMVYYLKP SSPKHVRFSW HQDAVTVTCS DLSYGDLLYE VQYRSPFDTE WQSKQENTCN VTIEGLDAEK CYSFWVRVKA MEDVYGPDTY PSDWSEVTCW QRGEIRDACA ETPTPPKPKL SK` Molecular weight: (232aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol Purity: >85% by SDS - PAGE State: Liquid purified protein Purified