Endothelin-2 (25-178, His-tag) - AR50825PU-N

Product Description for Endothelin-2

Endothelin-2.
Presentation: Purified

Immunogen	Swiss Prot Num: P20800
Purity	> 85 % by SDS - PAGE
Background	EDN2 is a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This protein is involved in a wide range of biological processes, such as hypertension and ovulation.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Bourgeois C., et al. (1997) J. Clin. Endocrinol. Metab. 82:3116-3123Ohkubo S., et al. (1990) FEBS Lett. 274:136-140
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human EDN2 protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSQAAATLE QPASSSHAQG THLRLRRCSC SSWLDKECVY FCHLDIIWVN TPEQTAPYGL GNPPRRRRRS LPRRCQCSSA RDPACATFCL RRPWTEAGAV PSRKSPADVF QTGKTGATTG ELLQRLRDIS TVKSLFAKRQ QEAMREPRST HSRWRKR` Molecular weight: (177aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol Purity: >85% by SDS - PAGE State: Liquid purified protein Purified