Product Description for FAM49B
FAM49B.
Presentation: Purified
Presentation: Purified
Properties for FAM49B
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Presentation | Purified |
| Molecular weight | 39.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | FAM49B has been provisionally designated FAM49B pending further characterization. In a recent genome-wide transcriptional analysis, It identified a gene signature for multiple sclerosis (MS), which reverted back to normal during pregnancy. Reversion was particularly evident for 7 genes: SOCS2, TNFAIP3, NR4A2, CXCR4, POLR2J, FAM49B, and STAG3L1, most of which encode negative regulators of inflammation. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Francesca Gilli. et al. (2011) Arch Neurol. 68:879-888Niranjana A Nagarajan. et al. (2012) Nature Immunology. 13:579–586. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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