Product Description for GULP1 / CED6
GULP1 / CED6.
Presentation: Purified
Presentation: Purified
Properties for GULP1 / CED6
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | CED-6, Cell death protein 6 homolog, PTB domain adapter protein CED-6, PTB domain-containing engulfment adapter protein 1 |
| Presentation | Purified |
| Molecular weight | 36.9 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 95 % by SDS - PAGE |
| Background | PTB domain-containing engulfment adapter protein 1, also known as GULP1, is an evolutionarily conserved adaptor protein required for efficient engulfment of apoptotic cells by phagocytes. GULP1 also helps modulate cellular glycosphingolipid and cholesterol transport. It also may play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GULP1 are associated with increases in cellular levels of GTP-bound ARF6. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Smits E., et al. (2000) Curr Biol. 9:1351-1354Su H P., et al. (2000) J Biol Chem. 275: 9542-9549. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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