Product Description for CD46 / MCP
CD46 / MCP.
Presentation: Purified
Presentation: Purified
Properties for CD46 / MCP
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen |
| Presentation | Purified |
| Molecular weight | 33.8 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1–4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Riley R C., et al. (2002) Mol Reprod Dev. 62:534-546.Iwata K., et al. (1995) J Biol Chem. 270:15148-15152. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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