AR50826PU-S NCEH1 / AADACL1 (1-275, His-tag)

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0.1 mg / €320.00
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NCEH1 / AADACL1

Product Description for NCEH1 / AADACL1

NCEH1 / AADACL1.
Presentation: Purified

Properties for NCEH1 / AADACL1

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms Arylacetamide deacetylase-like 1, KIAA1363, NCEH, Neutral cholesterol ester hydrolase 1
Presentation Purified
Molecular weight 33.6 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q6PIU2
Purity > 90 % by SDS - PAGE
Background Neutral cholesterol ester hydrolase 1, also known as NCEH1, hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. It may be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also NCEH1 is involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. This protein may contribute to cancer pathogenesis by promoting tumor cell migration.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Chiang K.P., et al. (2006) Chem. Biol. 13:1041-1050Okazaki H., et al. (2008) J. Biol. Chem. 283:33357-33364
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human NCEH1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMAEELNA VIVSIEYRLV PKVYFPEQIH DVVRATKYFL KPEVLQKYMV DPGRICISGD SAGGNLAAAL GQQFTQDASL KNKLKLQALI YPVLQALDFN TPSYQQNVNT PILPRYVMVK YWVDYFKGNY DFVQAMIVNN HTSLDVEEAA AVRARLNWTS LLPASFTKNY KPVVQTTGNA RIVQELPQLL DARSAPLIAD QAVLQLLPKT YILTCEHDVL RDDGIMYAKR LESAGVEVTL DHFEDGFHGC MIFTSWPTNF SVGIRTRNSY IKWLDQNL
Molecular weight:
(298aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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