Interleukin-34 / IL34 (21-242, His-tag) - AR50814PU-N

Product Description for Interleukin-34 / IL34

Interleukin-34 / IL34.
Presentation: Purified

Immunogen	Swiss Prot Num: Q6ZMJ4
Purity	> 85 % by SDS - PAGE
Background	IL34, also known as Interleukin 34, is a protein belonging to a group of cytokines called interleukins. This protein increases growth or survival of immune cells known as monocytes; it elicits its activity by binding the Colony stimulating factor 1 receptor. It also has a potential role in viral infection, the adaptive immune response and bone marrow cell proliferation.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Lin H. et al. (2008) Science. 320:807-811.Wang Y. et al. (2012) Nat Immunol. 13:753-760.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human IL34 protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMNE PLEMWPLTQN EECTVTGFLR DKLQYRSRLQ YMKHYFPINY KISVPYEGVF RIANVTRLQR AQVSERELRY LWVLVSLSAT ESVQDVLLEG HPSWKYLQEV QTLLLNVQQG LTDVEVSPKV ESVLSLLNAP GPNLKLVRPK ALLDNCFRVM ELLYCSCCKQ SSVLNWQDCE VPSPQSCSPE PSLQYAATQL YPPPPWSPSS PPHSTGSVRP VRAQGEGLLP` Molecular weight: (260aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea Purity: >85% by SDS - PAGE State: Liquid purified protein Purified