ID2 / BHLHB26 (1-134, His-tag) - AR50815PU-S

Product Description for ID2 / BHLHB26

ID2 / BHLHB26.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	Class B basic helix-loop-helix protein 26, DNA-binding protein inhibitor ID-2, Inhibitor of DNA binding 2
Presentation	Purified
Molecular weight	17.0 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q02363
Purity	> 85 % by SDS - PAGE
Background	ID2 belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Hara E. et al. (1994) J Biol Chem. 269:2139-2145.Langlands Ket al. (1997) J Biol Chem. 272:19785-19793.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human ID2 protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG` Molecular weight: (154aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea Purity: >85% by SDS - PAGE State: Liquid purified protein Purified