Product Description for Tomoregulin-1 / TMEFF1
Tomoregulin-1 / TMEFF1.
Presentation: Purified
Presentation: Purified
Properties for Tomoregulin-1 / TMEFF1
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | C9orf2, Transmembrane protein with EGF-like and one follistatin-like domain |
| Presentation | Purified |
| Molecular weight | 33.9 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | TMEFF1, also known as tomoregulin-1, is a type I transmembrane glycoprotein. This protein contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain of TMEFF1 can be released as a soluble protein. TMEFF1 is predominantly expressed in brain, but is downregulated in brain neoplasms. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Gery S, Yin D, et al. (2003). Oncogene. 22(18):2723-7.Harms PW, et al. (2003). Genes Dev. 17(21):2624-9. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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