17-beta-HSD1 / HSD17B1 (1-328, His-tag) - AR50925PU-S

Product Description for 17-beta-HSD1 / HSD17B1

17-beta-HSD1 / HSD17B1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	17-beta-hydroxysteroid dehydrogenase type 1, 17E2DH, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha HSD, E17KSR, EDH17B1, EDH17B2, EDHB17, Estradiol 17-beta-dehydrogenase 1, Placental 17-beta-hydroxysteroid dehydrogenase
Presentation	Purified
Molecular weight	37.5 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P14061
Purity	> 90 % by SDS - PAGE
Background	Estradiol 17-beta-dehydrogenase 1, also known as HSD17B1, belongs to the short-chain dehydrogenases/reductases (SDR) family. This protein favors the reduction of estrogens and androgens.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Qiu W., et al. (2002) FASEB J. 16:1829-1831Gangloff A. (2003) FASEB J. 17:274-276
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human HSD17B1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSHMARTVV LITGCSSGIG LHLAVRLASD PSQSFKVYAT LRDLKTQGRL WEAARALACP PGSLETLQLD VRDSKSVAAA RERVTEGRVD VLVCNAGLGL LGPLEALGED AVASVLDVNV VGTVRMLQAF LPDMKRRGSG RVLVTGSVGG LMGLPFNDVY CASKFALEGL CESLAVLLLP FGVHLSLIEC GPVHTAFMEK VLGSPEEVLD RTDIHTFHRF YQYLAHSKQV FREAAQNPEE VAEVFLTALR APKPTLRYFT TERFLPLLRM RLDDPSGSNY VTAMHREVFG DVPAKAEAGA EAGGGAGPGA EDEAGRGAVG DPELGDPPAA PQ` Molecular weight: (352aa) confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT Purity: >90% by SDS - PAGE State: Liquid purified protein Purified