Product Description for JDP2
JDP2.
Presentation: Purified
Presentation: Purified
Properties for JDP2
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 10 µg |
| Synonyms | Jun dimerization protein 2 |
| Presentation | Purified |
| Molecular weight | 21.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | Jun dimerization protein 2, also known as JDP2, is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. This protein is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. JDP2 can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. It may control transcription via direct regulation of the modification of histones and the assembly of chromatin. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Kawaida R., et al. (2003) J. Exp. Med. 197:1029-1035Jin C., et al. (2006) Nat. Struct. Mol. Biol. 13:331-338 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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