Nociceptin (20-176, His-tag) - AR50893PU-S

Product Description for Nociceptin

Nociceptin.
Presentation: Purified

Immunogen	Swiss Prot Num: Q13519
Purity	> 90 % by SDS - PAGE
Background	Prepronociceptin, also known as PNOC, is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. This protein may be involved in neuronal differentiation and development.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Fiset M.E., et al. (2003) Biochemistry. 42:10498-10505Nothacker H.-P., et al. (1996) Proc. Natl. Acad. Sci. U.S.A. 93:8677-8682
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human PNOC protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSSCQRDCL TCQEKLHPAL DSFDLEVCIL ECEEKVFPSP LWTPCTKVMA RSSWQLSPAA PEHVAAALYQ PRASEMQHLR RMPRVRSLFQ EQEEPEPGME EAGEMEQKQL QKRFGGFTGA RKSARKLANQ KRFSEFMRQY LVLSMQSSQR RRTLHQNGNV` Molecular weight: (180aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol Purity: >90% by SDS - PAGE State: Liquid purified protein Purified