POLE3 (1-147, His-tag) - AR50965PU-N

Product Description for POLE3

POLE3.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	Arsenic-transactivated protein, CHRAC17, Chromatin accessibility complex 17, DNA polymerase II subunit 3, DNA polymerase epsilon subunit 3, DNA polymerase epsilon subunit p17
Presentation	Purified
Molecular weight	19 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9NRF9
Purity	> 90 % by SDS - PAGE
Background	POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. PO
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Bolognese F, Imbriano C, et al. (2000). Nucleic Acids Res. 28(19):3830-8.Li Y, Pursell ZF, et al. (2000). J Biol Chem. 275(30):23247-52.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMAERPED LNLPNAVITR IIKEALPDGV NISKEARSAI SRAASVFVLY ATSCANNFAM KGKRKTLNAS DVLSAMEEME FQRFVTPLKE ALEAYRREQK GKKEASEQKK KDKDKKTDSE EQDKSRDEDN DEDEERLEEE EQNEEEEVDN` Molecular weight: (170aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 1mM DTT. Purity: >90% by SDS - PAGE State: Liquid purified protein Purified