PSTPIP1 / CD2BP1 (1-416, His-tag) - AR50982PU-S

Product Description for PSTPIP1 / CD2BP1

PSTPIP1 / CD2BP1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	CD2 antigen-binding protein 1, CD2 cytoplasmic tail-binding protein, CD2-binding protein 1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PEST phosphatase-interacting protein 1, PSTPIP, Proline-serine-threonine phosphatase-interacting protein 1
Presentation	Purified
Molecular weight	50.0 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: O43586
Purity	> 90 % by SDS - PAGE
Background	PSTPIP1 binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been sho
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Shoham N.G., et al. (2003) Proc. Natl. Acad. Sci. U.S.A. 100:13501-13506Wise C.A., et al. (2002) Hum. Mol. Genet. 11:961-969
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMMPQLQF KDAFWCRDFT AHTGYEVLLQ RLLDGRKMCK DMEELLRQRA QAEERYGKEL VQIARKAGGQ TEINSLRASF DSLKQQMENV GSSHIQLALT LREELRSLEE FRERQKEQRK KYEAVMDRVQ KSKLSLYKKA MESKKTYEQK CRDADDAEQA FERISANGHQ KQVEKSQNKA RQCKDSATEA ERVYRQSIAQ LEKVRAEWEQ EHRTTCEAFQ LQEFDRLTIL RNALWVHSNQ LSMQCVKDDE LYEEVRLTLE GCSIDADIDS FIQAKSTGTE PPAPVPYQNY YDREVTPLTS SPGIQPSCGM IKRFSGLLHG SPKTTSLAAS AASTETLTPT PERNEGVYTA IAVQEIQGNP ASPAQEYRAL YDYTAQNPDE LDLSAGDILE VILEGEDGWW TVERNGQRGF VPGSYLEKL` Molecular weight: (439aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT Purity: >90% by SDS - PAGE State: Liquid purified protein Purified