HLA class II DO alpha / HLA-DOA (26-217, His-tag) - AR51010PU-N

Product Description for HLA class II DO alpha / HLA-DOA

HLA class II DO alpha / HLA-DOA.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	HLA class II histocompatibility antigen DO alpha chain, HLA-DNA, HLA-DZA, MHC DN-alpha, MHC DZ alpha, MHC class II antigen DOA
Presentation	Purified
Molecular weight	24.1 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P06340
Purity	> 90 % by SDS - PAGE
Background	HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with cla
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Yoon,T., et al. (2012) Proc. Natl. Acad. Sci. U.S.A. 109 (28), 11276-11281Gieger,C., et al. (2012) Nature 480 (7376), 201-208
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSTKADHMG SYGPAFYQSY GASGQFTHEF DEEQLFSVDL KKSEAVWRLP EFGDFARFDP QGGLAGIAAI KAHLDILVER SNRSRAINVP PRVTVLPKSR VELGQPNILI CIVDNIFPPV INITWLRNGQ TVTEGVAQTS FYSQPDHLFR KFHYLPFVPS AEDVYDCQVE HWGLDAPLLR HWELQVPIPP PDAME` Molecular weight: (215aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol Purity: >90% by SDS - PAGE State: Liquid purified protein Purified