Product Description for GPNMB / HGFIN
GPNMB / HGFIN.
Presentation: Purified
Presentation: Purified
Properties for GPNMB / HGFIN
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Transmembrane glycoprotein HGFIN, Transmembrane glycoprotein NMB |
| Presentation | Purified |
| Molecular weight | 53.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. The protein shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. |
| Concentration | 1 mg/ml (determined by Bradford assay) |
| General Readings | Rose A.A., et al. (2010) PLoS ONE. 5:e12093-e12093Patel-Chamberlin M., et al. (2011) Kidney Int. 79:1138-1148 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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