POLD4 (1-107, His-tag) - AR51106PU-S

Product Description for POLD4

POLD4.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	20 µg
Synonyms	DNA polymerase delta subunit 4, DNA polymerase delta subunit p12, POLDS
Presentation	Purified
Molecular weight	14.8 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9HCU8
Purity	> 90 % by SDS - PAGE
Background	POLD4 is the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Taylor T.D., et al. (2006) Nature. 440:497-500Gerhard D.S., et al. (2004) Genome Res. 14:2121-2127
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human POLD4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMGRKRLI TDSYPVVKRR EGPAGHSKGE LAPELGEEPQ PRDEEEAELE LLRQFDLAWQ YGPCTGITRL QRWCRAKQMG LEPPPEVWQV LKTHPGDPRF QCSLWHLYPL` Molecular weight: (130aa) confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT Purity: >90% by SDS - PAGE State: Liquid purified protein Purified