Product Description for Uracil phosphoribosyltransferase (UPRT)
Uracil phosphoribosyltransferase (UPRT).
Presentation: Purified
Presentation: Purified
Properties for Uracil phosphoribosyltransferase (UPRT)
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | UMP pyrophosphorylase, UPRTase |
| Presentation | Purified |
| Molecular weight | 36.2 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | UPRT is a uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | T. Selwood and E. K. Jaffe. (2011) Arch. Biochem. Biophys. 519 (2): 131–43. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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