AR51146PU-S Fucosyltransferase 3 (35-361, His-tag)

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50 µg / €320.00
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Quick Overview

Fucosyltransferase 3

Product Description for Fucosyltransferase 3

Fucosyltransferase 3.
Presentation: Purified

Properties for Fucosyltransferase 3

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms Blood group Lewis alpha-4-fucosyltransferase, FT3B, FUT3, FucT-III, Fucosyltransferase III, Galactoside 3(4)-L-fucosyltransferase, LE, Lewis FT
Presentation Purified
Molecular weight 40.6 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P21217
Purity > 80 % by SDS - PAGE
Background Fucosyltransferase 3, also known as FUT3, may catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. This protein may be involved in blood group Lewis determination; Lewis-positive (Le+) individuals have an active enzyme while Lewis-negative (Le-) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links.
Concentration 1 mg/ml (determined by Bradford assay)
General Readings Cameron H.S., et al. (1995) J. Biol. Chem. 270:20112-20122Nishihara S., et al. (1993) Biochem. Biophys. Res. Commun. 196:624-631
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human FUT3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSRVSRDDA TGSPRAPSGS SRQDTTPTRP TLLILLWTWP FHIPVALSRC SEMVPGTADC HITADRKVYP QADTVIVHHW DIMSNPKSRL PPSPRPQGQR WIWFNLEPPP NCQHLEALDR YFNLTMSYRS DSDIFTPYGW LEPWSGQPAH PPLNLSAKTE LVAWAVSNWK PDSARVRYYQ SLQAHLKVDV YGRSHKPLPK GTMMETLSRY KFYLAFENSL HPDYITEKLW RNALEAWAVP VVLGPSRSNY ERFLPPDAFI HVDDFQSPKD LARYLQELDK DHARYLSYFR WRETLRPRSF SWALDFCKAC WKLQQESRYQ TVRSIAAWFT
Molecular weight:
(350aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Purity:
>80% by SDS - PAGE
State:
Liquid purified protein
Purified
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