PPP1R3B (1-285, His-tag) - AR51154PU-S

Product Description for PPP1R3B

PPP1R3B.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, PPP1R4, Protein phosphatase 1 regulatory subunit 3B, Protein phosphatase 1 regulatory subunit 4
Presentation	Purified
Molecular weight	35.1 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q86XI6
Purity	> 85 % by SDS - PAGE
Background	PPP1R3B is the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.
Concentration	1 mg/ml (determined by Bradford assay)
General Readings	Munro S., et al. (2005) Diabetes. 51:591-598Ota T., et al. (2004) Nat. Genet. 36:40-45
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human PPP1R3B protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMMAVDIE YRYNCMAPSL RQERFAFKIS PKPSKPLRPC IQLSSKNEAS GMVAPAVQEK KVKKRVSFAD NQGLALTMVK VFSEFDDPLD MPFNITELLD NIVSLTTAES ESFVLDFSQP SADYLDFRNR LQADHVCLEN CVLKDKAIAG TVKVQNLAFE KTVKIRMTFD TWKSYTDFPC QYVKDTYAGS DRDTFSFDIS LPEKIQSYER MEFAVYYECN GQTYWDSNRG KNYRIIRAEL KSTQGMTKPH SGPDLGISFD QFGSPRCSYG LFPEWPSYLG YEKLGPYY` Molecular weight: (308aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol Purity: >85% by SDS - PAGE State: Liquid purified protein Purified