ASB8 (1-288, His-tag) - AR51165PU-S

Product Description for ASB8

ASB8.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	20 µg
Synonyms	ASB-8, Ankyrin repeat and SOCS box protein 8
Presentation	Purified
Molecular weight	.0 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9H765
Purity	> 90 % by SDS - PAGE
Background	Ankyrin repeat and SOCS box containing 8, also known as ASB8, may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Liu Y., et al. (2003) Biochem. Biophys. Res. Commun. 300:972-979Ota T., et al. (2004) Nat. Genet. 36:40-45
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human ASB8 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMSSSMWY IMQSIQSKYS LSERLIRTIA AIRSFPHDNV EDLIRGGADV NCTHGTLKPL HCACMVSDAD CVELLLEKGA EVNALDGYNR TALHYAAEKD EACVEVLLEY GANPNALDGN RDTPLHWAAF KNNAECVRAL LESGASVNAL DYNNDTPLSW AAMKGNLESV SILLDYGAEV RVINLIGQTP ISRLVALLVR GLGTEKEDSC FELLHRAVGH FELRKNGTMP REVARDPQLC EKLTVLCSAP GTLKTLARYA VRRSLGLQYL PDAVKGLPLP ASLKEYLLLL E` Molecular weight: (311aa) confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT Purity: >90% by SDS - PAGE State: Liquid purified protein Purified