DUSP26 (1-211, His-tag) - AR51148PU-S

Product Description for DUSP26

DUSP26.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	DUSP24, Dual specificity phosphatase SKRP3, Dual specificity protein phosphatase 26, LDP4, Low-molecular-mass dual-specificity phosphatase 4, MKP8, Mitogen-activated protein kinase phosphatase 8, NATA1, Novel amplified gene in thyroid anaplastic cancer, SKRP3
Presentation	Purified
Molecular weight	26.3 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9BV47
Purity	> 85 % by SDS - PAGE
Background	DUSP26 inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. This protein inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. DUSP26 can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Vasudevan S.A.. et al. (2005). Biochem. Biophys. Res. Commun. 330:511-518Yu W., et al. (2007). Oncogene 26:1178-1187
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human DUSP26 protein, fused to His-tag at N-terminus, was expressed in E.coli . AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMCPGNWL WASMTFMARF SRSSSRSPVR TRGTLEEMPT VQHPFLNVFE LERLLYTGKT ACNHADEVWP GLYLGDQDMA NNRRELRRLG ITHVLNASHS RWRGTPEAYE GLGIRYLGVE AHDSPAFDMS IHFQTAADFI HRALSQPGGK ILVHCAVGVS RSATLVLAYL MLYHHLTLVE AIKKVKDHRG IIPNRGFLRQ LLALDRRLRQ GLEA` Molecular weight: (234aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea Purity: >85% by SDS - PAGE State: Liquid purified protein Purified