Sprouty homolog 4 / SPRY4 (1-299, His-tag) - AR51150PU-S

Product Description for Sprouty homolog 4 / SPRY4

Sprouty homolog 4 / SPRY4.
Presentation: Purified

Immunogen	Swiss Prot Num: Q9C004
Purity	> 85 % by SDS - PAGE
Background	SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS.
Concentration	1mg/ml (determined by Bradford assay)
General Readings	Katoh Y, Katoh M. (2006). Int J Mol Med 17 (3): 529–32
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human SPRY4 protein, fused to His-tag at N-terminus, was expressed in E.coli . AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMEPPIPQ SAPLTPNSVM VQPLLDSRMS HSRLQHPLTI LPIDQVKTSH VENDYIDNPS LALTTGPKRT RGGAPELAPT PARCDQDVTH HWISFSGRPS SVSSSSSTSS DQRLLDHMAP PPVADQASPR AVRIQPKVVH CQPLDLKGPA VPPELDKHFL LCEACGKCKC KECASPRTLP SCWVCNQECL CSAQTLVNYG TCMCLVQGIF YHCTNEDDEG SCADHPCSCS RSNCCARWSF MGALSVVLPC LLCYLPATGC VKLAQRGYDR LRRPGCRCKH TNSVICKAAS GDAKTSRPDK PF` Molecular weight: (322aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea Purity: >85% by SDS - PAGE State: Liquid purified protein Purified