GAGE2A (1-116, His-tag) - AR51161PU-N

Product Description for GAGE2A

GAGE2A.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.5 mg
Synonyms	CT4.2, G antigen 2A/2B, GAGE-2, GAGE-2A, GAGE2
Presentation	Purified
Molecular weight	15 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q6NT46
Purity	> 90 % by SDS - PAGE
Background	GAGE2A belongs to a multigene family expressed in a large variety of tumors whereas in normal tissues, expression is restricted to germ cells. These genes organized in clustered repeats, have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Gjerstorff MF, et al. (2008). Tissue Antigens.71(3):187-92. De Backer O, Arden KC, et al. (1999). Cancer Res. 59(13):3157-65.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human GAGE2A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMSWRGRS TYRPRPRRYV EPPEMIGPMR PEQFSDEVEP ATPEEGEPAT QRQDPAAAQE GQDEGASAGQ GPKPEAHSQE QGHPQTGCEC EDGPDGQEMD PPNPEEVKTP EEGEKQSQC` Molecular weight: (139aa) confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT. Purity: >90% by SDS - PAGE State: Liquid purified protein Purified