Product Description for PLSCR3
PLSCR3.
Presentation: Purified
Presentation: Purified
Properties for PLSCR3
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | Ca(2+)-dependent phospholipid scramblase 3, PL scramblase 3, Phospholipid scramblase 3 |
| Presentation | Purified |
| Molecular weight | 30.9 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | PLSCR3 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. This protein may play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. It seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | He Y., et al (2007), J. Cell. Biochem. 101:1210-1221 Shibata H., et al 2008) J. Biol. Chem. 283:9623-9632 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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