Product Description for QKI / Protein quaking
QKI / Protein quaking.
Presentation: Purified
Presentation: Purified
Properties for QKI / Protein quaking
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | HKQ, QK1, QK3 |
| Presentation | Purified |
| Molecular weight | 40.1 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | Protein quaking isoform HQK-5, also known as QKI, is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. It is involved in myelinization and oligodendrocyte differentiation, and it may play a role in schizophrenia. Defects or deletions in the QKI are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings | Hardy R J., et al. (1996) J Neurosci. 16: 7941-7949. Ebersole T A., et al. (1996) Nat Genet. 12: 260-265. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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