AR51238PU-N ST3GAL5 (83-418, His-tag)

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0.5 mg / €820.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

ST3GAL5

Product Description for ST3GAL5

ST3GAL5.
Presentation: Purified

Properties for ST3GAL5

Product Category Proteins & Growth Factors
Quantity 0.5 mg
Synonyms 3-sialyltransferase, CMP-NeuAc:lactosylceramide alpha-2, Ganglioside GM3 synthase, Lactosylceramide alpha-2, SIAT9, ST3Gal V, ST3GalV, Sialyltransferase 9
Presentation Purified
Molecular weight 41.0 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9UNP4
Purity > 85 % by SDS - PAGE
Background Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Berselli P., Zava S.. et al. (2006). Biochim. Biophys. Acta 1759:348-358
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human ST3GAL5 protein, fused to His-tag at N-terminus, was expressed in E.coli .
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSLKLNYTT EECDMKKMHY VDPDHVKRAQ KYAQQVLQKE CRPKFAKTSM ALLFEHRYSV DLLPFVQKAP KDSEAESKYD PPFGFRKFSS KVQTLLELLP EHDLPEHLKA KTCRRCVVIG SGGILHGLEL GHTLNQFDVV IRLNSAPVEG YSEHVGNKTT IRMTYPEGAP LSDLEYYSND LFVAVLFKSV DFNWLQAMVK KETLPFWVRL FFWKQVAEKI PLQPKHFRIL NPVIIKETAF DILQYSEPQS RFWGRDKNVP TIGVIAVVLA THLCDEVSLA GFGYDLNQPR TPLHYFDSQC MAAMNFQTMH NVTTETKFLL KLVKEGVVKD LSGGIDREF
Molecular weight:
(359aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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