MDS1 (1-169, His-tag) - AR51246PU-S

Product Description for MDS1

MDS1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	20 µg
Synonyms	MDS1-EVI1, Myelodysplasia syndrome 1, PRDM3
Presentation	Purified
Molecular weight	21.1 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q6FH90
Purity	> 85 % by SDS - PAGE
Background	MDS1 is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. Recombinant human MDS1 protein, fused to His-tag at N-terminus, was expressed in E.coli
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Fears S., et al. (1996) Proc. Natl. Acad. Sci. U.S.A. 93:1642-1647.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSMRSKGRA RKLATNNECV YGNYPEIPLE EMPDADGVAS TPSLNIQEPC SPATSSEAFT PKEGSPYKAP IYIPDDIPIP AEFELRESNM PGAGLGIWTK RKIEVGEKFG PYVGEQRSNL KDPSYGWEVH LPRSRRVSVH SWLYLGKRSS DVGIAFSQAD VYMPGLQCAF LS` Molecular weight: (192aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea Purity: >85% by SDS - PAGE State: Liquid purified protein Purified