Thyrotropin beta chain (21-138, His-tag) - AR51247PU-N

Product Description for Thyrotropin beta chain

Thyrotropin beta chain.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.1 mg
Synonyms	TSH, TSH beta, TSHB, Thyroid-stimulating hormone subunit beta, Thyrotropin subunit beta
Presentation	Purified
Molecular weight	15.9 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P01222
Purity	> 85 % by SDS - PAGE
Background	The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimmers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. TSHB is the beta subunit of thyroid stimulating hormone. Mutations in this gene result in congenital hypothyroidism. Recombinant human TSHB protein, fused to His-tag at N-terminus, was expressed in E.coli
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Hayashizaki Y., Miyai K.. et al. (1985). FEBS Lett. 188:394-400
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSFCIPTEY TMHIERRECA YCLTINTTIC AGYCMTRDIN GKLFLPKYAL SQDVCTYRDF IYRTVEIPGC PLHVAPYFSY PVALSCKCGK CNTDYSDCIH EAIKTNYCTK PQKSYLVGFS V` Molecular weight: (141aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea Purity: >85% by SDS - PAGE State: Liquid purified protein Purified