Product Description for FAM84B
FAM84B.
Presentation: Purified
Presentation: Purified
Properties for FAM84B
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | BCMP101, Breast cancer membrane protein 101, NSE2, Protein NSE2 |
| Presentation | Purified |
| Molecular weight | 36.9 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
|
|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | FAM84B, as known as Family with sequence similarity 84, member B, coprecipitated with a downstream effector of RAS, CRAF. Binding of FAM83B with CRAF disrupted CRAF/14-3-3 interactions and increased CRAF membrane localization, resulting in elevated MAPK and mammalian target of rapamycin (mTOR) signaling. It is an oncogene and potentially represents a new target for therapeutic intervention. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Kraja AT. et al. (2013) Lipids. 48:155-165 Camps J. et al. (2009) Genes Chromosomes Cancer. 48:1002-1017. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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