AR51287PU-N Methionine aminopeptidase 1D / MAP1D (20-335, His-tag)

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0.25 mg / €1,070.00
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Quick Overview

Methionine aminopeptidase 1D / MAP1D

Product Description for Methionine aminopeptidase 1D / MAP1D

Methionine aminopeptidase 1D / MAP1D.
Presentation: Purified

Properties for Methionine aminopeptidase 1D / MAP1D

Product Category Proteins & Growth Factors
Quantity 0.25 mg
Presentation Purified
Molecular weight 37.4 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q6UB28
Purity > 85 % by SDS - PAGE
Background Methionine aminopeptidase 1D, mitochondrial precursor, also known as METAP1D, is a 335 amino acid mitochondrial protein that belongs to the peptidase M24A family. It is overexpressed in colon cancer cell lines, suggesting a role in tumorigenesis. METAP1D has also been found to remove methionine from the N-terminus of nascent proteins. METAP1D binds two cobalt ions per subunit and is encoded by a gene that maps to human chromosome 2q31.1.
Concentration 0.25mg/ml (determined by Bradford assay)
General Readings Leszczyniecka M., et al. (2006) Oncogene. 25: 3471-3478.
Serero A., et al. (2003) J Biol Chem. 278: 52953-52963.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human METAP1D protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSSSPLNHI YLHKQSSSQQ RRNFFFRRQR DISHSIVLPA AVSSAHPVPK HIKKPDYVTT GIVPDWGDSI EVKNEDQIQG LHQACQLARH VLLLAGKSLK VDMTTEEIDA LVHREIISHN AYPSPLGYGG FPKSVCTSVN NVLCHGIPDS RPLQDGDIIN IDVTVYYNGY HGDTSETFLV GNVDECGKKL VEVARRCRDE AIAACRAGAP FSVIGNTISH ITHQNGFQVC PHFVGHGIGS YFHGHPEIWH HANDSDLPME EGMAFTIEPI ITEGSPEFKV LEDAWTVVSL DNQRSAQFEH TVLITSRGAQ ILTKLPHEA
Molecular weight:
(339aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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