Product Description for Malcavernin
Malcavernin.
Presentation: Purified
Presentation: Purified
Properties for Malcavernin
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | C7orf22, CCM2, Cerebral cavernous malformations 2 protein, PP10187 |
| Presentation | Purified |
| Molecular weight | 34.3 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | CCM2 provides instructions for making a protein called malcavernin, which strengthens the interactions between cells that form blood vessels and limits leakage from the vessels. It interacts with a number of other proteins to form a complex that is found in the junctions that connect neighboring cells. It helps turn off (suppress) a signaling molecule known as RhoA-GTPase. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Dupre N. et al. (2003) Can J Neurol Sci. 30:122-128 Liquori CL. et al. (2007) Am J Hum Genet. 80:69-75. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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