DEFB118 (21-123, His-tag) - AR51273PU-N

Product Description for DEFB118

DEFB118.
Presentation: Purified

Immunogen	Swiss Prot Num: Q96PH6
Purity	> 90 % by SDS - PAGE
Background	DEFB118 is a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity. This protein is found in a cluster with other beta-defensin genes on the long arm of chromosome 20.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Kao CY, Chen Y, et al. (2003). Am J Respir Cell Mol Biol. 29(1):71-80. Schutte BC, Mitros JP, et al. (2002). Proc Natl Acad Sci U S A. 99(4):2129-33.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human DEFB118 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSYSGEKKC WNRSGHCRKQ CKDGEAVKDT CKNLRACCIP SNEDHRRVPA TSPTPLSDST PGIIDDILTV RFTTDYFEVS SKKDMVEESE AGRGTETSLP NVHHSS` Molecular weight: (126aa), confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT. Purity: >90% by SDS - PAGE State: Liquid purified protein Purified