Product Description for SEC61B
SEC61B.
Presentation: Purified
Presentation: Purified
Properties for SEC61B
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | Protein transport protein Sec61 subunit beta |
| Presentation | Purified |
| Molecular weight | 9.4 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. |
| Concentration | 0.25mg/ml (determined by Bradford assay) |
| General Readings | Bebox Z., et al. (1998) J Biol Chem. 273: 29873-29878. Meyer H A., et al. (2000) J Biol Chem. 275: 14550-14557. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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