AR51393PU-S Calreticulin-3 (20-384, His-tag)

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0.1 mg / €320.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Calreticulin-3

Product Description for Calreticulin-3

Calreticulin-3.
Presentation: Purified

Properties for Calreticulin-3

Product Category Proteins & Growth Factors
Quantity 0.1 mg
Synonyms CALR3, CRT2, Calreticulin-2
Presentation Purified
Molecular weight 43 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q96L12
Purity > 90 % by SDS - PAGE
Background Calreticulin 3, also known as CALR3, is a member of the calreticulin (CRT) family. It is calcium-binding chaperones that are localized to the endoplasmic reticulum or sarcoplasmic reticulum in eukaryotes. CALR3 assists in the calreticulin/calnexin cycle, where it is involved in protein-folding, oligomeric assembly and quality control in the ER. With specific expression in testis, CALR3 has been implicated as a cancer-testis antigen due to its frequent expression in various cancers.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Persson S., et al. (2002) Gene. 297: 151-158.
Michalak M., et al. (1998) Biochem Cell Biol. 76: 779-785.
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human CALR3 protein was expressed in E.coli.
AA Sequence:
MTVYFQEEFL DGEHWRNRWL QSTNDSRFGH FRLSSGKFYG HKEKDKGLQT TQNGRFYAIS ARFKPFSNKG KTLVIQYTVK HEQKMDCGGG YIKVFPADID QKNLNGKSQY YIMFGPDICG FDIKKVHVIL HFKNKYHENK KLIRCKVDGF THLYTLILRP DLSYDVKIDG QSIESGSIEY DWNLTSLKKE TSPAESKDWE QTKDNKAQDW EKHFLDASTS KQSDWNGDLD GDWPAPMLQK PPYQDGLKPE GIHKDVWLHR KMKNTDYLTQ YDLSEFENIG AIGLELWQVR SGTIFDNFLI TDDEEYADNF GKATWGETKG PEREMDAIQA KEEMKKAREE EEEELLSGKI NRHEHYFNQF HRRNEL
Molecular weight:
(366aa)
Format
Buffer System:
20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Purity:
>90% by SDS - PAGE
State:
Liquid purified protein
Purified
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