TGFBRAP1 / TRAP1 (601-860, His-tag) - AR51408PU-N

Product Description for TGFBRAP1 / TRAP1

TGFBRAP1 / TRAP1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	TGF-beta receptor-associated protein 1, TRAP-1, Transforming growth factor-beta receptor-associated protein 1
Presentation	Purified
Molecular weight	33 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q8WUH2
Purity	> 80 % by SDS - PAGE
Background	TGFBRAP1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. It may recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Felts SJ, Owen BA, et al. (2000). J Biol Chem. 275(5):3305-12. Simmons AD, Musy MM, et al. (1999). Hum Mol Genet. 8(12):2155-64.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human TGFBRAP1 protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKRLQ KEEYHTHLAV LYLEEVLLQR ASASGKGAEA TETQAKLRRL LQKSDLYRVH FLLERLQGAG LPMESAILHG KLGEHEKALH ILVHELQDFA AAEDYCLWCS EGRDPPHRQQ LFHTLLAIYL HAGPTAHELA VAAVDLLNRH ATEFDAAQVL QMLPDTWSVQ LLCPFLMGAM RDSIHARRTM QVALGLARSE NLIYTYDKMK LKGSSIQLSD KKLCQICQNP FCEPVFVRYP NGGLVHTHCA ASRHTNPSSS SPGTRT` Molecular weight: (269aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol Purity: >80% by SDS - PAGE State: Liquid purified protein Purified