Product Description for Complement factor B
Complement factor B.
Presentation: Purified
Presentation: Purified
Properties for Complement factor B
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B |
| Presentation | Purified |
| Molecular weight | 28.4 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Immunogen |
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|---|---|
| Purity | > 85 % by SDS - PAGE |
| Background | CFB is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Mejia J.E., et al (1994). Hum. Immunol. 39:49-53 Schwaeble W., et al (1993). Immunobiology 188:221-232 |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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