Product Description for GSK3 beta
GSK3 beta.
Presentation: Purified
Presentation: Purified
Properties for GSK3 beta
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.25 mg |
| Synonyms | GSK-3 beta, GSK3B, Glycogen synthase kinase-3 beta |
| Presentation | Purified |
| Molecular weight | 46 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 85 % by SDS - PAGE |
| Background | GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Guo X, Ramirez A, et al. (2008). Genes Dev. 22(1):106-20. Espinosa L, Inglés-Esteve J, et al. (2003). J Biol Chem. 278(34):32227-35. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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