AR51370PU-S KLF6 (1-283, His-tag)

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50 µg / €400.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

KLF6

Product Description for KLF6

KLF6.
Presentation: Purified

Properties for KLF6

Product Category Proteins & Growth Factors
Quantity 50 µg
Synonyms B-cell-derived protein 1, BCD1, COPEB, CPBP, Core promoter element-binding protein, GC-rich sites-binding factor GBF, KLF6, Krueppel-like factor 6, Proto-oncogene BCD1, ST12, Transcription factor Zf9
Presentation Purified
Molecular weight 34.3 kDa
Source E. coli
Species (Protein) Human
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Proteins (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q99612
Purity > 85 % by SDS - PAGE
Background KLF6, also known as Krueppel-like factor 6, is a nuclear protein that has three zinc fingers. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters.
Concentration 1.0 mg/ml (determined by Bradford assay)
General Readings Narla G. et al. (2003) Am J Pathol. 162:1047-1052.
Narla G. et al. (2001) Science. 294:2563-2566
Storage Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description
Description:
Recombinant human KLF6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMDVLPMC SIFQELQIVH ETGYFSALPS LEEYWQQTCL ELERYLQSEP CYVSASEIKF DSQEDLWTKI ILAREKKEES ELKISSSPPE DTLISPSFCY NLETNSLNSD VSSESSDSSE ELSPTAKFTS DPIGEVLVSS GKLSSSVTST PPSSPELSRE PSQLWGCVPG ELPSPGKVRS GTSGKPGDKG NGDASPDGRR RVHRCHFNGC RKVYTKSSHL KAHQRTHTGE KPYRCSWEGC EWRFARSDEL TRHFRKHTGA KPFKCSHCDR CFSRSDHLAL HMKRHL
Molecular weight:
(306aa) confirmed by MALDI-TOF
Format
Buffer System:
20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol 1mM DTT
Purity:
>85% by SDS - PAGE
State:
Liquid purified protein
Purified
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