Product Description for Neuronal acetylcholine receptor subunit alpha-6
Neuronal acetylcholine receptor subunit alpha-6.
Presentation: Purified
Presentation: Purified
Properties for Neuronal acetylcholine receptor subunit alpha-6
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | CHRNA6, Nicotinic acetylcholine receptor subunit alpha-6 |
| Presentation | Purified |
| Molecular weight | 29.3 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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| Purity | > 85 % by SDS - PAGE |
| Background | Cholinergic receptor, nicotinic, alpha 6, also known as CHRNA6, belongs to the nicotinic acetylcholine receptors (nAChRs) family. nAChRs are heteropentameric ligand-gated ion channels resulting from the assembly of alpha and beta protein subunits. This ion channel is gated by the binding of acetylcholine to the assembled receptor. Alpha 6 is often found associated with beta 3, beta 2, and alpha 4 subunits. CHRNA6 receptors have a relatively selective localization to the nigrostriatal pathway where they function to mediate dopamine release. |
| Concentration | 1.0 mg/ml (determined by Bradford assay) |
| General Readings | Keskitalo Vuokko k., et al. (2011) Nicotine Tob Res. 13(8): 686-90. Groot Kormrlink P J., et al. (2004) J Gen Physiol. 123: 697-708. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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