Product Description for GET4
GET4.
Presentation: Purified
Presentation: Purified
Properties for GET4
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 0.5 mg |
| Synonyms | C7orf20, CEE, CGI-20, Conserved edge-expressed protein, Golgi to ER traffic protein 4 homolog, TRC35, Transmembrane domain recognition complex 35 kDa subunit |
| Presentation | Purified |
| Molecular weight | 38.9 kDa |
| Source | E. coli |
| Species (Protein) | Human |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
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|---|---|
| Purity | > 90 % by SDS - PAGE |
| Background | GET4 is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting. |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| General Readings | Mariappan M., Li X., et al. (2010) Nature 466:1120-1124. |
| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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