BRMS1 (1-246, T7 tag) - AR51322PU-S

Product Description for BRMS1

BRMS1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	20 µg
Synonyms	Breast cancer metastasis-suppressor 1
Presentation	Purified
Molecular weight	29.9 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: Q9HCU9
Purity	> 80 % by SDS - PAGE
Background	BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Meehan W.J., et al. (2004) J. Biol. Chem. 279:1562-1569.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human BRMS1 protein, fused to His-tag at N-terminus, was expressed in E.coli . AA Sequence: `MASMTGGQQM GRGSHMPVQP PSKDTEEMEA EGDSAAEMNG EEEESEEERS GSQTESEEES SEMDDEDYER RRSECVSEML DLEKQFSELK EKLFRERLSQ LRLRLEEVGA ERAPEYTEPL GGLQRSLKIR IQVAGIYKGF CLDVIRNKYE CELQGAKQHL ESEKLLLYDT LQGELQERIQ RLEEDRQSLD LSSEWWDDKL HARGSSRSWD SLPPSKRKKA PLVSGPYIVY MLQEIDILED WTAIKKARAA VSPQKRKSDG P` Molecular weight: (261aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea Purity: >80% by SDS - PAGE State: Liquid purified protein Purified