BCAR1 / CRKAS (465-848, His-tag) - AR51358PU-S

Product Description for BCAR1 / CRKAS

BCAR1 / CRKAS.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	Breast cancer anti-estrogen resistance protein 1, CASS1, CRK-associated substrate, Cas scaffolding protein family member 1, p130cas, p130cas
Presentation	Purified
Molecular weight	43.9 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P56945
Purity	> 85 % by SDS - PAGE
Background	BCAR1, or CAS, is an Src family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion.
Concentration	0.5 mg/ml (determined by Bradford assay)
General Readings	Konstantinovsky,S, et al. (2012) Clin. Exp. Metastasis 29 (6), 527-540 Huang,W., et al. (2012) PLoS ONE 7 (4), E36124
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human BCAR1 protein, fused to His-tag at N-terminus, was expressed in E.coli. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSRLQQGVS ATVAHLLDLA GSAGATGSWR SPSEPQEPLV QDLQAAVAAV QSAVHELLEF ARSAVGNAAH TSDRALHAKL SRQLQKMEDV HQTLVAHGQA LDAGRGGSGA TLEDLDRLVA CSRAVPEDAK QLASFLHGNA SLLFRRTKAT APGPEGGGTL HPNPTDKTSS IQSRPLPSPP KFTSQDSPDG QYENSEGGWM EDYDYVHLQG KEEFEKTQKE LLEKGSITRQ GKSQLELQQL KQFERLEQEV SRPIDHDLAN WTPAQPLAPG RTGGLGPSDR QLLLFYLEQC EANLTTLTNA VDAFFTAVAT NQPPKIFVAH SKFVILSAHK LVFIGDTLSR QAKAADVRSQ VTHYSNLLCD LLRGIVATTK AAALQYPSPS AAQDMVE` Molecular weight: (407aa)
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol Purity: >85% by SDS - PAGE State: Liquid purified protein Purified