DFFA / ICAD (C-term) - SP1235P | acris-antibodies.com

Product Description for DFFA / ICAD

Rabbit anti Mouse DFFA / ICAD.
Properties: (C-term)
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Product Category	Primary Antibodies
Quantity	0.1 mg
Synonyms	DFF-45, DFF1, DFF45, DNA fragmentation factor 45 kDa subunit, DNA fragmentation factor subunit alpha, Inhibitor of CAD
Presentation	Purified
Reactivity	Ms
Applications	WB
Clonality	Polyclonal
Host	Rabbit
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Immunogen	Swiss Prot Num: O54786 Immunogen: Synthetic peptide corresponding to amino acids 312-331 of mouse ICAD GeneID: 13347
Property	C-term
Application	Western blot: 1/500 - 1/1000; this antibody recognises a 45kD band in Western blots.
Background	ICAD (Inhibitor of Caspase-Activated DNase) is the murine homologue of human DFF-45. ICAD is cleaved by Caspase-3, releasing CAD which eventually causes degradation of DNA in the nucleus.
Concentration	0.5 mg/ml
General Readings	Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature. 1998 Jan 1;391(6662):43-50. PubMed PMID: 9422506. Sakahira H, Enari M, Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature. 1998 Jan 1;391(6662):96-9. PubMed PMID: 9422513. Wyllie, A. (1998) Apoptosis: An endonuclease at last. Nature 391: 20-21.
Storage	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	Purification: Affinity chromatography Buffer System: PBS containing 0.02% Sodium Azide State: Liquid purified IgG Purified
Specificity	Specificity: This antibody reacts to ICAD. Species: Mouse.

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