PF4V1 (31-104, His-tag) - AR51475PU-N

Product Description for PF4V1

PF4V1.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	0.25 mg
Synonyms	C-X-C motif chemokine 4 variant, CXCL4L1, CXCL4V1, PF4alt, PF4var1, Platelet factor 4 variant, SCYB4V1
Presentation	Purified
Molecular weight	10.6 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P10720
Purity	> 85 % by SDS - PAGE
Background	PF4V1 belongs to the intercrine alpha (chemokine CxC) family. It is a inhibitor of angiogenesis and inhibitor of endothelial cell chemotaxis(in vitro). Binding to heparin is much weaker than in the close homolog PF4/CXCL4.
Concentration	0.25 mg/ml (determined by Bradford assay)
General Readings	Green CJ, Charles RS, et al. (1989). Mol Cell Biol. 9(4):1445-51.Eisman R, Surrey S, et al. (1990). Blood. 76(2):336-44.Struyf S, Burdick MD, et al. (2004). Circ Res. 95(9):855-7.Kuo JH, Chen YP, et al. (2013). J Biol Chem. 288(19):13522-33.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human PF4V1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSFARAEAE EDGDLQCLCV KTTSQVRPRH ITSLEVIKAG PHCPTAQLIA TLKNGRKICL DLQALLYKKI IKEHLES` Molecular weight: (97aa) confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 1mM DTT. Purity: >85% by SDS - PAGE State: Liquid purified protein Purified