Product Description for HCV NS5B
HCV NS5B.
Presentation: Purified
Presentation: Purified
Properties for HCV NS5B
| Product Category | Proteins & Growth Factors |
|---|---|
| Quantity | 50 µg |
| Synonyms | Hepatitis C Virus, RNA-directed RNA polymerase NS5B |
| Presentation | Purified |
| Molecular weight | 17.0 kDa |
| Source | E. coli |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | OriGene Technologies GmbH |
| Material safety datasheet | MSDS for Proteins (de) |
Datasheet Extract
| Purity | > 90 % by SDS - PAGE |
|---|---|
| Background | Hepatitis C virus genotype 1 is a core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. It modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit and also regulates many host cellular functions such as signaling pathways and apoptosis. It prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| General Readings |
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| Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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