M6PR (27-185, His-tag) - AR51495PU-S

Product Description for M6PR

M6PR.
Presentation: Purified

Product Category	Proteins & Growth Factors
Quantity	50 µg
Synonyms	46 kDa mannose 6-phosphate receptor, CD Man-6-P receptor, CD-MPR, Cation-dependent mannose-6-phosphate receptor, MPR46, MPRD
Presentation	Purified
Molecular weight	20.3 kDa
Source	E. coli
Species (Protein)	Human
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	OriGene Technologies GmbH
Material safety datasheet	MSDS for Proteins (de)

Immunogen	Swiss Prot Num: P20645
Purity	> 85 % by SDS - PAGE
Background	M6PR is a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. This protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.
Concentration	0.5 mg/ml (determined by BRADFORD assay)
General Readings	Prabakaran T, Nielsen R., et al. (2012) PLoS One. 2012;7(6):e39975.
Storage	Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Description	Description: Recombinant human M6PR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.. AA Sequence: `MGSSHHHHHH SSGLVPRGSH MGSTEEKTCD LVGEKGKESE KELALVKRLK PLFNKSFEST VGQGSDTYIY IFRVCREAGN HTSGAGLVQI NKSNGKETVV GRLNETHIFN GSNWIMLIYK GGDEYDNHCG KEQRRAVVMI SCNRHTLADN FNPVSEERGK VQDCFYLFEM DSSLACSPEI SH` Molecular weight: (182aa) confirmed by MALDI-TOF
Format	Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT Purity: >85% by SDS - PAGE State: Liquid purified protein Purified